Endocrine Abstracts

Background: A fetal macrosomia is the most frequent complication of gestational diabetes mellitus (GDM) in Lithuania. The aim of our study was to assess the predicting factors of fetal macrosomia in GDM.Methods: Retrospective data analysis of 3 547 women who delivered in Vilnius University Hospital Santariskiu Klinikos in 2015 was performed. Documented GDM risk factors were obtained from medical records and electronic database. Newborns over 4000 g birth...

Introduction: Adrenocortical carcinomas (ACC) are rare and frequently aggressive tumors that may be functional (hormone-secreting) – causing Cushing’s syndrome and/or virilization, or nonfunctional – presenting as an abdominal mass or as an incidental finding. We describe a rare case of stage IV adrenocortical carcinoma which first manifested as treatment resistant Cushing’s syndrome.Case report: In september of 2021, a 24-year-old fe...

Introduction: Weakness is one of the most common complaints among the patients. Clinical manifestations of a hypopituitarism depend on the extent of hormone deficiency and may be non-specific and thus the diagnosis is often missed. The progressive loss of pituitary hormone secretion is usually a slow process, which can occur over a period of months or years.Clinical case: A 62 years old women who complained of mild weakness mostly in the evenings in the ...

Introduction: Thyrotoxic periodic paralysis (TPP) is very rare (prevalence in non-Asian populations 0.1–0.2%, more frequent in men) and potentially life-threatening complication of hyperthyroidism. TPP develops when thyroid hormones cause sodium-potassium-adenosine triphosphatase (Na/K-ATPase) pump overactivity, leading to rapid potassium shift into the cells resulting in hypokalaemia. This causes transient episode of muscular weakness usually involving lower limbs and hy...